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Selective C-Rel Activation via Malt1 Controls Anti-Fungal T(H)-17 Immunity by Dectin-1 and Dectin-2

C-type lectins dectin-1 and dectin-2 on dendritic cells elicit protective immunity against fungal infections through induction of T(H)1 and T(H)-17 cellular responses. Fungal recognition by dectin-1 on human dendritic cells engages the CARD9-Bcl10-Malt1 module to activate NF-κB. Here we demonstrate...

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Detalles Bibliográficos
Autores principales: Gringhuis, Sonja I., Wevers, Brigitte A., Kaptein, Tanja M., van Capel, Toni M. M., Theelen, Bart, Boekhout, Teun, de Jong, Esther C., Geijtenbeek, Teunis B. H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024268/
https://www.ncbi.nlm.nih.gov/pubmed/21283787
http://dx.doi.org/10.1371/journal.ppat.1001259