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Down-regulation of phosphoglucomutase 3 mediates sulforaphane-induced cell death in LNCaP prostate cancer cells

BACKGROUND: Sulforaphane (SFN) is an isothiocyanate found in cruciferous vegetables that exerts anti-oxidant, anti-inflammatory, anti-cancer and radio-sensitizing activities. Nonetheless, the mechanism responsible for SFN-induced cell death is not fully understood. In the present study, anti-cancer...

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Detalles Bibliográficos
Autores principales: Lee, Chan-Hee, Jeong, Soo-Jin, Yun, Sun-Mi, Kim, Ji-Hyun, Lee, Hyo-Jung, Ahn, Kwang Seok, Won, Suk-Hyun, Kim, Hyun Seok, Lee, Hyo-Jeong, Ahn, Kyoo-Seok, Zhu, Shudong, Chen, Chang-Yan, Kim, Sung-Hoon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024296/
https://www.ncbi.nlm.nih.gov/pubmed/21159204
http://dx.doi.org/10.1186/1477-5956-8-67