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Evolutionary and Structural Features of the C2, V3 and C3 Envelope Regions Underlying the Differences in HIV-1 and HIV-2 Biology and Infection

BACKGROUND: Unlike in HIV-1 infection, the majority of HIV-2 patients produce broadly reactive neutralizing antibodies, control viral replication and survive as elite controllers. The identification of the molecular, structural and evolutionary footprints underlying these very distinct immunological...

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Detalles Bibliográficos
Autores principales: Barroso, Helena, Borrego, Pedro, Bártolo, Inês, Marcelino, José Maria, Família, Carlos, Quintas, Alexandre, Taveira, Nuno
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024314/
https://www.ncbi.nlm.nih.gov/pubmed/21283793
http://dx.doi.org/10.1371/journal.pone.0014548