Impact of KRAS, BRAF, PIK3CA Mutations, PTEN, AREG, EREG Expression and Skin Rash in ≥2(nd) Line Cetuximab-Based Therapy of Colorectal Cancer Patients

BACKGROUND: To investigate the predictive significance of KRAS, BRAF, PIK3CA mutational status, AREG- EREG mRNA expression, PTEN protein expression and skin rash in metastatic colorectal cancer (mCRC) patients treated with cetuximab containing salvage chemotherapy. METHODS: Primary tumors from 112 m...

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Detalles Bibliográficos
Autores principales: Saridaki, Zacharenia, Tzardi, Maria, Papadaki, Chara, Sfakianaki, Maria, Pega, Fraga, Kalikaki, Aristea, Tsakalaki, Eleftheria, Trypaki, Maria, Messaritakis, Ippokratis, Stathopoulos, Efstathios, Mavroudis, Dimitris, Georgoulias, Vassilis, Souglakos, John
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024325/
https://www.ncbi.nlm.nih.gov/pubmed/21283802
http://dx.doi.org/10.1371/journal.pone.0015980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024325/
https://www.ncbi.nlm.nih.gov/pubmed/21283802
http://dx.doi.org/10.1371/journal.pone.0015980

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