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Low HDL Cholesterol, Metformin Use, and Cancer Risk in Type 2 Diabetes: The Hong Kong Diabetes Registry

OBJECTIVE: The AMP-activated protein kinase (AMPK) pathway is a master regulator in energy metabolism and may be related to cancer. In type 2 diabetes, low HDL cholesterol predicts cancer, whereas metformin usage is associated with reduced cancer risk. Both metformin and apolipoprotein A1 activate t...

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Detalles Bibliográficos
Autores principales: Yang, Xilin, So, Wing Yee, Ma, Ronald C.W., Kong, Alice P.S., Lee, Heung Man, Yu, Linda W.L., Chow, Chun-Chung, Ozaki, Risa, Ko, Gary T.C., Chan, Juliana C.N.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024352/
https://www.ncbi.nlm.nih.gov/pubmed/20980414
http://dx.doi.org/10.2337/dc10-1509