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Activation of MyD88 Signaling upon Staphylococcal Enterotoxin Binding to MHC Class II Molecules

Ligands binding to Toll-like receptor (TLR), interleukin 1 receptor (IL-1R), or IFN-γR1 are known to trigger MyD88-mediated signaling, which activates pro-inflammatory cytokine responses. Recently we reported that staphylococcal enterotoxins (SEA or SEB), which bind to MHC class II molecules on APCs...

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Detalles Bibliográficos
Autores principales: Kissner, Teri L., Ruthel, Gordon, Alam, Shahabuddin, Ulrich, Robert G., Fernandez, Stefan, Saikh, Kamal U.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024394/
https://www.ncbi.nlm.nih.gov/pubmed/21283748
http://dx.doi.org/10.1371/journal.pone.0015985