Hypoxia Potentiates Glioma-Mediated Immunosuppression

Glioblastoma multiforme (GBM) is a lethal cancer that exerts potent immune suppression. Hypoxia is a predominant feature of GBM, but it is unclear to the degree in which tumor hypoxia contributes to this tumor-mediated immunosuppression. Utilizing GBM associated cancer stem cells (gCSCs) as a treatm...

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Detalles Bibliográficos
Autores principales: Wei, Jun, Wu, Adam, Kong, Ling-Yuan, Wang, Yongtao, Fuller, Gregory, Fokt, Isabella, Melillo, Giovanni, Priebe, Waldemar, Heimberger, Amy B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024401/
https://www.ncbi.nlm.nih.gov/pubmed/21283755
http://dx.doi.org/10.1371/journal.pone.0016195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024401/
https://www.ncbi.nlm.nih.gov/pubmed/21283755
http://dx.doi.org/10.1371/journal.pone.0016195

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