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Hypoxia Potentiates Glioma-Mediated Immunosuppression
Glioblastoma multiforme (GBM) is a lethal cancer that exerts potent immune suppression. Hypoxia is a predominant feature of GBM, but it is unclear to the degree in which tumor hypoxia contributes to this tumor-mediated immunosuppression. Utilizing GBM associated cancer stem cells (gCSCs) as a treatm...
Autores principales: | Wei, Jun, Wu, Adam, Kong, Ling-Yuan, Wang, Yongtao, Fuller, Gregory, Fokt, Isabella, Melillo, Giovanni, Priebe, Waldemar, Heimberger, Amy B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024401/ https://www.ncbi.nlm.nih.gov/pubmed/21283755 http://dx.doi.org/10.1371/journal.pone.0016195 |
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