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Chronic Respiratory Aeroallergen Exposure in Mice Induces Epithelial-Mesenchymal Transition in the Large Airways

Chronic allergic asthma is characterized by Th2-polarized inflammation and leads to airway remodeling and fibrosis but the mechanisms involved are not clear. To determine whether epithelial-mesenchymal transition contributes to airway remodeling in asthma, we induced allergic airway inflammation in...

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Detalles Bibliográficos
Autores principales: Johnson, Jill R., Roos, Abraham, Berg, Tove, Nord, Magnus, Fuxe, Jonas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024415/
https://www.ncbi.nlm.nih.gov/pubmed/21283768
http://dx.doi.org/10.1371/journal.pone.0016175