Suppression of Osteosarcoma Cell Invasion by Chemotherapy Is Mediated by Urokinase Plasminogen Activator Activity via Up-Regulation of EGR1

BACKGROUND: The cellular and molecular mechanisms of tumour response following chemotherapy are largely unknown. We found that low dose anti-tumour agents up-regulate early growth response 1 (EGR1) expression. EGR1 is a member of the immediate-early gene group of transcription factors which modulate...

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Detalles Bibliográficos
Autores principales: Matsunoshita, Yukihiro, Ijiri, Kosei, Ishidou, Yasuhiro, Nagano, Satoshi, Yamamoto, Takuya, Nagao, Hiroko, Komiya, Setsuro, Setoguchi, Takao
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024416/
https://www.ncbi.nlm.nih.gov/pubmed/21283769
http://dx.doi.org/10.1371/journal.pone.0016234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024416/
https://www.ncbi.nlm.nih.gov/pubmed/21283769
http://dx.doi.org/10.1371/journal.pone.0016234

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