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ReCLIP (Reversible Cross-Link Immuno-Precipitation): An Efficient Method for Interrogation of Labile Protein Complexes

The difficulty of maintaining intact protein complexes while minimizing non-specific background remains a significant limitation in proteomic studies. Labile interactions, such as the interaction between p120-catenin and the E-cadherin complex, are particularly challenging. Using the cadherin comple...

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Detalles Bibliográficos
Autores principales: Smith, Andrew L., Friedman, David B., Yu, Huapeng, Carnahan, Robert H., Reynolds, Albert B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024417/
https://www.ncbi.nlm.nih.gov/pubmed/21283770
http://dx.doi.org/10.1371/journal.pone.0016206