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HIV-1 Enhancing Effect of Prostatic Acid Phosphatase Peptides Is Reduced in Human Seminal Plasma

We recently reported that HIV-1 infection can be inhibited by innate antimicrobial components of human seminal plasma (SP). Conversely, naturally occurring peptidic fragments from the SP-derived prostatic acid phosphatase (PAP) have been reported to form amyloid fibrils called “SEVI” and enhance HIV...

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Detalles Bibliográficos
Autores principales: Martellini, Julie A., Cole, Amy L., Svoboda, Pavel, Stuchlik, Olga, Chen, Li-Mei, Chai, Karl X., Gangrade, Bhushan K., Sørensen, Ole E., Pohl, Jan, Cole, Alexander M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024420/
https://www.ncbi.nlm.nih.gov/pubmed/21283773
http://dx.doi.org/10.1371/journal.pone.0016285