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The Mammalian Class 3 PI3K (PIK3C3) Is Required for Early Embryogenesis and Cell Proliferation

The Pik3c3 gene encodes an 887 amino acid lipid kinase, phosphoinositide-3-kinase class 3 (PIK3C3). PIK3C3 is known to regulate various intracellular membrane trafficking events. However, little is known about its functions during early embryogenesis in mammals. To investigate the function of PIK3C3...

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Detalles Bibliográficos
Autores principales: Zhou, Xiang, Takatoh, Jun, Wang, Fan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024421/
https://www.ncbi.nlm.nih.gov/pubmed/21283715
http://dx.doi.org/10.1371/journal.pone.0016358