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The Antioxidant Protein Peroxiredoxin 4 Is Epigenetically Down Regulated in Acute Promyelocytic Leukemia

The antioxidant peroxiredoxin (PRDX) protein family comprises 6 members, which are implicated in a variety of cellular responses, including growth factor signal transduction. PRDX4 resides in the endoplasmic reticulum (ER), where it locally controls oxidative stress by reducing H(2)O(2) levels. We r...

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Detalles Bibliográficos
Autores principales: Palande, Karishma K., Beekman, Renee, van der Meeren, Lotte E., Beverloo, H. Berna, Valk, Peter J. M., Touw, Ivo P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024432/
https://www.ncbi.nlm.nih.gov/pubmed/21283726
http://dx.doi.org/10.1371/journal.pone.0016340