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Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors

With the aim to identify cyclin B1-derived peptides with high affinity for HLA-A2, we used three in silico prediction algorithms to screen the protein sequence for possible HLA-A2 binders. One peptide scored highest in all three algorithms, and the high HLA-A2-binding affinity of this peptide was ve...

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Detalles Bibliográficos
Autores principales: Andersen, Rikke Sick, Sørensen, Rikke Bæk, Ritter, Cathrin, Svane, Inge Marie, Becker, Jürgen C., thor Straten, Per, Andersen, Mads Hald
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024510/
https://www.ncbi.nlm.nih.gov/pubmed/20981424
http://dx.doi.org/10.1007/s00262-010-0933-y