FOXA1 is a critical determinant of Estrogen Receptor function and endocrine response

Estrogen Receptor-α (ER) is the key feature in the majority of breast cancers and ER binding to the genome correlates with the Forkhead protein FOXA1 (HNF3α). We now show that FOXA1 is a critical determinant that can influence differential ER-chromatin interactions. We show that almost all ER-chroma...

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Detalles Bibliográficos
Autores principales: Hurtado, Antoni, Holmes, Kelly A., Ross-Innes, Caryn S., Schmidt, Dominic, Carroll, Jason S.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024537/
https://www.ncbi.nlm.nih.gov/pubmed/21151129
http://dx.doi.org/10.1038/ng.730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024537/
https://www.ncbi.nlm.nih.gov/pubmed/21151129
http://dx.doi.org/10.1038/ng.730

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