Human Perforin Employs Different Avenues to Damage Membranes

Perforin (PFN) is a pore-forming protein produced by cytotoxic lymphocytes that aids in the clearance of tumor or virus-infected cells by a mechanism that involves the formation of transmembrane pores. The properties of PFN pores and the mechanism of their assembly remain unclear. Here, we studied p...

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Detalles Bibliográficos
Autores principales: Praper, Tilen, Sonnen, Andreas, Viero, Gabriella, Kladnik, Aleš, Froelich, Christopher J., Anderluh, Gregor, Dalla Serra, Mauro, Gilbert, Robert J. C.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024789/
https://www.ncbi.nlm.nih.gov/pubmed/20889983
http://dx.doi.org/10.1074/jbc.M110.169417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024789/
https://www.ncbi.nlm.nih.gov/pubmed/20889983
http://dx.doi.org/10.1074/jbc.M110.169417

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