A Small Ribosomal Subunit (SSU) Processome Component, the Human U3 Protein 14A (hUTP14A) Binds p53 and Promotes p53 Degradation

Ribosome biogenesis is required for normal cell function, and aberrant ribosome biogenesis can lead to p53 activation. However, how p53 is activated by defects of ribosome biogenesis remains to be determined. Here, we identified human UTP14a as an SSU processome component by showing that hUTP14a is...

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Detalles Bibliográficos
Autores principales: Hu, Lelin, Wang, Jiangnan, Liu, Yun, Zhang, Ying, Zhang, Liangliang, Kong, Ruirui, Zheng, Zongfang, Du, Xiaojuan, Ke, Yang
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024804/
https://www.ncbi.nlm.nih.gov/pubmed/21078665
http://dx.doi.org/10.1074/jbc.M110.157842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024804/
https://www.ncbi.nlm.nih.gov/pubmed/21078665
http://dx.doi.org/10.1074/jbc.M110.157842

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