Cargando…

T-cell production of matrix metalloproteinases and inhibition of parasite clearance by TIMP-1 during chronic Toxoplasma infection in the brain

Chronic infection with the intracellular protozoan parasite Toxoplasma gondii leads to tissue remodelling in the brain and a continuous requirement for peripheral leucocyte migration within the CNS (central nervous system). In the present study, we investigate the role of MMPs (matrix metalloprotein...

Descripción completa

Detalles Bibliográficos
Autores principales: Clark, Robin T, Philip Nance, J, Noor, Shahani, Wilson, Emma H
Formato: Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024837/
https://www.ncbi.nlm.nih.gov/pubmed/21434872
http://dx.doi.org/10.1042/AN20100027