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T-cell production of matrix metalloproteinases and inhibition of parasite clearance by TIMP-1 during chronic Toxoplasma infection in the brain
Chronic infection with the intracellular protozoan parasite Toxoplasma gondii leads to tissue remodelling in the brain and a continuous requirement for peripheral leucocyte migration within the CNS (central nervous system). In the present study, we investigate the role of MMPs (matrix metalloprotein...
Autores principales: | Clark, Robin T, Philip Nance, J, Noor, Shahani, Wilson, Emma H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Neurochemistry
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024837/ https://www.ncbi.nlm.nih.gov/pubmed/21434872 http://dx.doi.org/10.1042/AN20100027 |
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