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Signal transduction in neurons: effects of cellular prion protein on fyn kinase and ERK1/2 kinase
BACKGROUND: It has been reported that cellular prion protein (PrP(c)) co-localizes with caveolin-1 and participates to signal transduction events by recruiting Fyn kinase. As PrP(c) is a secreted protein anchored to the outer surface membrane through a glycosylphosphatidylinositol (GPI) anchor ((sec...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024879/ https://www.ncbi.nlm.nih.gov/pubmed/21172064 http://dx.doi.org/10.1186/1742-4933-7-S1-S5 |