Cargando…

A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype

BACKGROUND: The dorsal thalamus acts as a gateway and modulator for information going to and from the cerebral cortex. This activity requires the formation of reciprocal topographic axon connections between thalamus and cortex. The axons grow along a complex multistep pathway, making sharp turns, cr...

Descripción completa

Detalles Bibliográficos
Autores principales: Dwyer, Noelle D, Manning, Danielle K, Moran, Jennifer L, Mudbhary, Raksha, Fleming, Michael S, Favero, Carlita B, Vock, Vita M, O'Leary, Dennis DM, Walsh, Christopher A, Beier, David R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024922/
https://www.ncbi.nlm.nih.gov/pubmed/21214893
http://dx.doi.org/10.1186/1749-8104-6-3