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SPABBATS: A pathway-discovery method based on Boolean satisfiability that facilitates the characterization of suppressor mutants

BACKGROUND: Several computational methods exist to suggest rational genetic interventions that improve the productivity of industrial strains. Nonetheless, these methods are less effective to predict possible genetic responses of the strain after the intervention. This problem requires a better unde...

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Detalles Bibliográficos
Autores principales: Flórez, Lope A, Gunka, Katrin, Polanía, Rafael, Tholen, Stefan, Stülke, Jörg
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024933/
https://www.ncbi.nlm.nih.gov/pubmed/21219666
http://dx.doi.org/10.1186/1752-0509-5-5