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SPABBATS: A pathway-discovery method based on Boolean satisfiability that facilitates the characterization of suppressor mutants
BACKGROUND: Several computational methods exist to suggest rational genetic interventions that improve the productivity of industrial strains. Nonetheless, these methods are less effective to predict possible genetic responses of the strain after the intervention. This problem requires a better unde...
Autores principales: | Flórez, Lope A, Gunka, Katrin, Polanía, Rafael, Tholen, Stefan, Stülke, Jörg |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024933/ https://www.ncbi.nlm.nih.gov/pubmed/21219666 http://dx.doi.org/10.1186/1752-0509-5-5 |
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