Some ABCA3 mutations elevate ER stress and initiate apoptosis of lung epithelial cells

BACKGROUND: ABCA3 transporter (ATP-binding cassette transporter of the A subfamily) is localized to the limiting membrane of lamellar bodies, organelles for assembly and storage of pulmonary surfactant in alveolar epithelial type II cells (AECII). It transports surfactant phospholipids into lamellar...

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Detalles Bibliográficos
Autores principales: Weichert, Nina, Kaltenborn, Eva, Hector, Andreas, Woischnik, Markus, Schams, Andrea, Holzinger, Andreas, Kern, Sunčana, Griese, Matthias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024939/
https://www.ncbi.nlm.nih.gov/pubmed/21214890
http://dx.doi.org/10.1186/1465-9921-12-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024939/
https://www.ncbi.nlm.nih.gov/pubmed/21214890
http://dx.doi.org/10.1186/1465-9921-12-4

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