Prime immunization with rotavirus VLP 2/6 followed by boosting with an adenovirus expressing VP6 induces protective immunization against rotavirus in mice

BACKGROUND: Rotavirus (RV) is the main cause of severe gastroenteritis in children. An effective vaccination regime against RV can substantially reduce morbidity and mortality. Previous studies have demonstrated the efficacy of virus-like particles formed by RV VP2 and VP6 (VLP2/6), as well as that...

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Detalles Bibliográficos
Autores principales: Zhou, Hongli, Guo, Li, Wang, Min, Qu, Jianguo, Zhao, Zhendong, Wang, Jianwei, Hung, Tao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024956/
https://www.ncbi.nlm.nih.gov/pubmed/21205330
http://dx.doi.org/10.1186/1743-422X-8-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024956/
https://www.ncbi.nlm.nih.gov/pubmed/21205330
http://dx.doi.org/10.1186/1743-422X-8-3

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