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BMP Signaling Modulates Hepcidin Expression in Zebrafish Embryos Independent of Hemojuvelin

Hemojuvelin (Hjv), a member of the repulsive-guidance molecule (RGM) family, upregulates transcription of the iron regulatory hormone hepcidin by activating the bone morphogenetic protein (BMP) signaling pathway in mammalian cells. Mammalian models have identified furin, neogenin, and matriptase-2 a...

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Detalles Bibliográficos
Autores principales: Gibert, Yann, Lattanzi, Victoria J., Zhen, Aileen W., Vedder, Lea, Brunet, Frédéric, Faasse, Sarah A., Babitt, Jodie L., Lin, Herbert Y., Hammerschmidt, Matthias, Fraenkel, Paula G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024971/
https://www.ncbi.nlm.nih.gov/pubmed/21283739
http://dx.doi.org/10.1371/journal.pone.0014553