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BMP Signaling Modulates Hepcidin Expression in Zebrafish Embryos Independent of Hemojuvelin
Hemojuvelin (Hjv), a member of the repulsive-guidance molecule (RGM) family, upregulates transcription of the iron regulatory hormone hepcidin by activating the bone morphogenetic protein (BMP) signaling pathway in mammalian cells. Mammalian models have identified furin, neogenin, and matriptase-2 a...
Autores principales: | Gibert, Yann, Lattanzi, Victoria J., Zhen, Aileen W., Vedder, Lea, Brunet, Frédéric, Faasse, Sarah A., Babitt, Jodie L., Lin, Herbert Y., Hammerschmidt, Matthias, Fraenkel, Paula G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024971/ https://www.ncbi.nlm.nih.gov/pubmed/21283739 http://dx.doi.org/10.1371/journal.pone.0014553 |
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