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Increased expression of PIN1 gene in papillary thyroid carcinoma

BACKGROUND: Peptidyl-prolyl cis/trans isomerase (Pin1), encoded by PIN1 gene with locus in chromosome 19p13, is an enzyme that catalytically induces conformational changes in proteins after phosphorylation on serine or threonine residues preceding proline (pSer/Thr-Pro motifs); in this way, it has a...

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Detalles Bibliográficos
Autores principales: Lewiński, Andrzej, Brzeziańska, Ewa, Czarnecka, Karolina, Latek, Joanna, Koptas, Włodzimierz, Cyniak-Magierska, Anna
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024986/
https://www.ncbi.nlm.nih.gov/pubmed/21219594
http://dx.doi.org/10.1186/1756-6614-4-4