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Shb deficient mice display an augmented T(H)2 response in peripheral CD4+ T cells
BACKGROUND: Shb, a ubiquitously expressed Src homology 2 domain-containing adaptor protein has previously been implicated in the signaling of various tyrosine kinase receptors including the TCR. Shb associates with SLP76, LAT and Vav, all important components in the signaling cascade governing T cel...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024994/ https://www.ncbi.nlm.nih.gov/pubmed/21223549 http://dx.doi.org/10.1186/1471-2172-12-3 |