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Shb deficient mice display an augmented T(H)2 response in peripheral CD4+ T cells

BACKGROUND: Shb, a ubiquitously expressed Src homology 2 domain-containing adaptor protein has previously been implicated in the signaling of various tyrosine kinase receptors including the TCR. Shb associates with SLP76, LAT and Vav, all important components in the signaling cascade governing T cel...

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Detalles Bibliográficos
Autores principales:	Gustafsson, Karin, Calounova, Gabriela, Hjelm, Fredrik, Kriz, Vitezslav, Heyman, Birgitta, Grönvik, Kjell-Olov, Mostoslavsky, Gustavo, Welsh, Michael
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024994/ https://www.ncbi.nlm.nih.gov/pubmed/21223549 http://dx.doi.org/10.1186/1471-2172-12-3

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