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Effect of erythromycin and rifampicin on monoethylglycinexylidide test
BACKGROUND: The dynamic liver function test based on the hepatic conversion of lidocaine to monoethylglycinexylidide (MEGX) provides a direct measure of the actual functional state of the liver. Cytochrome P450 (CYP) 3A4 has been proposed as the main CYP isoform responsible for MEGX formation. The c...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Medknow Publications
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025132/ https://www.ncbi.nlm.nih.gov/pubmed/21279172 http://dx.doi.org/10.4103/0253-7613.41044 |