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Targeting of tumor radioiodine therapy by expression of the sodium iodide symporter under control of the survivin promoter

To test the feasibility of using the survivin promoter to induce specific expression of sodium/iodide symporter (NIS) in cancer cell lines and tumors for targeted use of radionuclide therapy, a recombinant adenovirus, Ad-SUR-NIS, that expressed the NIS gene under control of the survivin promoter was...

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Detalles Bibliográficos
Autores principales: Huang, R, Zhao, Z, Ma, X, Li, S, Gong, R, Kuang, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025317/
https://www.ncbi.nlm.nih.gov/pubmed/21037556
http://dx.doi.org/10.1038/cgt.2010.66