Nanog Overcomes Reprogramming Barriers and Induces Pluripotency in Minimal Conditions

Induced pluripotency requires the expression of defined factors and culture conditions that support the self-renewal of embryonic stem (ES) cells [1]. Small molecule inhibition of MAP kinase (MEK) and glycogen synthase kinase 3 (GSK3) with LIF (2i/LIF) provides an optimal culture environment for mou...

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Detalles Bibliográficos
Autores principales: Theunissen, Thorold W., van Oosten, Anouk L., Castelo-Branco, Gonçalo, Hall, John, Smith, Austin, Silva, José C.R.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025321/
https://www.ncbi.nlm.nih.gov/pubmed/21194951
http://dx.doi.org/10.1016/j.cub.2010.11.074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025321/
https://www.ncbi.nlm.nih.gov/pubmed/21194951
http://dx.doi.org/10.1016/j.cub.2010.11.074

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