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Determination of ciprofloxacin in human plasma using high-performance liquid chromatography coupled with fluorescence detection: Application to a population pharmacokinetics study in children with severe malnutrition

Clinical pharmacokinetic studies of ciprofloxacin require accurate and precise measurement of plasma drug concentrations. We describe a rapid, selective and sensitive HPLC method coupled with fluorescence detection for determination of ciprofloxacin in human plasma. Internal standard (IS; sarafloxac...

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Detalles Bibliográficos
Autores principales: Muchohi, Simon N., Thuo, Nahashon, Karisa, Japhet, Muturi, Alex, Kokwaro, Gilbert O., Maitland, Kathryn
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025326/
https://www.ncbi.nlm.nih.gov/pubmed/21185790
http://dx.doi.org/10.1016/j.jchromb.2010.11.032