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Structure–function relationships of the antigenicity of mycolic acids in tuberculosis patients

Cell wall mycolic acids (MA) from Mycobacterium tuberculosis (M.tb) are CD1b presented antigens that can be used to detect antibodies as surrogate markers of active TB, even in HIV coinfected patients. The use of the complex mixtures of natural MA is complicated by an apparent antibody cross-reactiv...

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Detalles Bibliográficos
Autores principales: Beukes, Mervyn, Lemmer, Yolandy, Deysel, Madrey, Al Dulayymi, Juma’a R., Baird, Mark S., Koza, Gani, Iglesias, Maximiliano M., Rowles, Richard R., Theunissen, Cornelia, Grooten, Johan, Toschi, Gianna, Roberts, Vanessa V., Pilcher, Lynne, Van Wyngaardt, Sandra, Mathebula, Nsovo, Balogun, Mohammed, Stoltz, Anton C., Verschoor, Jan A.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science Ireland Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025329/
https://www.ncbi.nlm.nih.gov/pubmed/20875402
http://dx.doi.org/10.1016/j.chemphyslip.2010.09.006