Crystal Structures of Penicillin-Binding Protein 3 from Pseudomonas aeruginosa: Comparison of Native and Antibiotic-Bound Forms

We report the first crystal structures of a penicillin-binding protein (PBP), PBP3, from Pseudomonas aeruginosa in native form and covalently linked to two important β-lactam antibiotics, carbenicillin and ceftazidime. Overall, the structures of apo and acyl complexes are very similar; however, vari...

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Detalles Bibliográficos
Autores principales: Sainsbury, Sarah, Bird, Louise, Rao, Vincenzo, Shepherd, Sharon M., Stuart, David I., Hunter, William N., Owens, Raymond J., Ren, Jingshan
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025346/
https://www.ncbi.nlm.nih.gov/pubmed/20974151
http://dx.doi.org/10.1016/j.jmb.2010.10.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025346/
https://www.ncbi.nlm.nih.gov/pubmed/20974151
http://dx.doi.org/10.1016/j.jmb.2010.10.024

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