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Bacteroides fragilis RecA protein overexpression causes resistance to metronidazole

Bacteroides fragilis is a human gut commensal and an opportunistic pathogen causing anaerobic abscesses and bacteraemias which are treated with metronidazole (Mtz), a DNA damaging agent. This study examined the role of the DNA repair protein, RecA, in maintaining endogenous DNA stability and its con...

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Detalles Bibliográficos
Autores principales: Steffens, Laura S., Nicholson, Samantha, Paul, Lynthia V., Nord, Carl Erik, Patrick, Sheila, Abratt, Valerie R.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025348/
https://www.ncbi.nlm.nih.gov/pubmed/20435137
http://dx.doi.org/10.1016/j.resmic.2010.04.003