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Regulation of Cisplatin Cytotoxicity by Cu Influx Transporters

Platinum drugs are an important class of cancer chemotherapeutics. However, the use of these drugs is limited by the development of resistance during treatment with decreased accumulation being a common mechanism. Both Cu transporters CTR1 and CTR2 influence the uptake and cytotoxicity of cisplatin....

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Detalles Bibliográficos
Autores principales: Abada, Paolo, Howell, Stephen B.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025362/
https://www.ncbi.nlm.nih.gov/pubmed/21274436
http://dx.doi.org/10.1155/2010/317581