ERK/p90(RSK)/14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicúa

Compounds that inhibit signalling upstream of ERK (extracellular-signal-regulated kinase) are promising anticancer therapies, motivating research to define how this pathway promotes cancers. In the present study, we show that human capicúa represses mRNA expression for PEA3 (polyoma enhancer activat...

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Detalles Bibliográficos
Autores principales: Dissanayake, Kumara, Toth, Rachel, Blakey, Jamie, Olsson, Olof, Campbell, David G., Prescott, Alan R., MacKintosh, Carol
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025492/
https://www.ncbi.nlm.nih.gov/pubmed/21087211
http://dx.doi.org/10.1042/BJ20101562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025492/
https://www.ncbi.nlm.nih.gov/pubmed/21087211
http://dx.doi.org/10.1042/BJ20101562

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