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HIV-1 RT-dependent DNAzyme expression inhibits HIV-1 replication without the emergence of escape viruses
DNAzymes are easier to prepare and less sensitive to chemical and enzymatic degradation than ribozymes; however, a DNA enzyme expression system has not yet been developed. In this study, we exploited the mechanism of HIV-1 reverse transcription (RT) in a DNA enzyme expression system. We constructed...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025543/ https://www.ncbi.nlm.nih.gov/pubmed/20833635 http://dx.doi.org/10.1093/nar/gkq794 |