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Determinants of eukaryal cell killing by the bacterial ribotoxin PrrC

tRNA damage inflicted by the Escherichia coli anticodon nuclease PrrC (EcoPrrC) underlies an antiviral response to phage T4 infection. PrrC homologs are present in many bacterial proteomes, though their biological activities are uncharted. PrrCs consist of two domains: an N-terminal NTPase module re...

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Detalles Bibliográficos
Autores principales: Meineke, Birthe, Schwer, Beate, Schaffrath, Raffael, Shuman, Stewart
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025547/
https://www.ncbi.nlm.nih.gov/pubmed/20855293
http://dx.doi.org/10.1093/nar/gkq831