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Tonicity-responsive microRNAs contribute to the maximal induction of osmoregulatory transcription factor OREBP in response to high-NaCl hypertonicity

Osmotic response element binding protein (OREBP) is a Rel-like transcription factor critical for cellular osmoresponses. Previous studies suggest that hypertonicity-induced accumulation of OREBP protein might be mediated by transcription activation as well as posttranscriptional mRNA stabilization o...

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Detalles Bibliográficos
Autores principales: Huang, Weifeng, Liu, Huili, Wang, Tao, Zhang, Tiantian, Kuang, Juntao, Luo, Yu, Chung, Stephen S. M., Yuan, Li, Yang, James Y.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025551/
https://www.ncbi.nlm.nih.gov/pubmed/20852262
http://dx.doi.org/10.1093/nar/gkq818