Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases

Higher eukaryotes encode various Y-family DNA polymerases to perform global DNA lesion bypass. To provide complete mutation spectra for abasic lesion bypass, we employed short oligonucleotide sequencing assays to determine the sequences of abasic lesion bypass products synthesized by human Y-family...

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Detalles Bibliográficos
Autores principales: Sherrer, Shanen M., Fiala, Kevin A., Fowler, Jason D., Newmister, Sean A., Pryor, John M., Suo, Zucai
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025555/
https://www.ncbi.nlm.nih.gov/pubmed/20846959
http://dx.doi.org/10.1093/nar/gkq719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025555/
https://www.ncbi.nlm.nih.gov/pubmed/20846959
http://dx.doi.org/10.1093/nar/gkq719

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