Walking of antitumor bifunctional trinuclear Pt(II) complex on double-helical DNA

The trinuclear BBR3464 ([{trans-PtCl(NH(3))(2)}(2)µ-(trans-Pt(NH(3))(2)(H(2)N(CH(2))(6)NH(2))(2))](4+)) belongs to the polynuclear class of platinum-based anticancer agents. DNA adducts of this complex differ significantly in structure and type from those of clinically used mononuclear platinum comp...

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Detalles Bibliográficos
Autores principales: Malina, Jaroslav, Kasparkova, Jana, Farrell, Nicholas P., Brabec, Viktor
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025560/
https://www.ncbi.nlm.nih.gov/pubmed/20833634
http://dx.doi.org/10.1093/nar/gkq803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025560/
https://www.ncbi.nlm.nih.gov/pubmed/20833634
http://dx.doi.org/10.1093/nar/gkq803

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