Accurate quantification of transcriptome from RNA-Seq data by effective length normalization

We propose a novel, efficient and intuitive approach of estimating mRNA abundances from the whole transcriptome shotgun sequencing (RNA-Seq) data. Our method, NEUMA (Normalization by Expected Uniquely Mappable Area), is based on effective length normalization using uniquely mappable areas of gene an...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Soohyun, Seo, Chae Hwa, Lim, Byungho, Yang, Jin Ok, Oh, Jeongsu, Kim, Minjin, Lee, Sooncheol, Lee, Byungwook, Kang, Changwon, Lee, Sanghyuk
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025570/
https://www.ncbi.nlm.nih.gov/pubmed/21059678
http://dx.doi.org/10.1093/nar/gkq1015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025570/
https://www.ncbi.nlm.nih.gov/pubmed/21059678
http://dx.doi.org/10.1093/nar/gkq1015

Ejemplares similares