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Role of transcript and interplay between transcription and replication in triplet-repeat instability in mammalian cells
Triplet-repeat expansions cause several inherited human diseases. Expanded triplet-repeats are unstable in somatic cells, and tissue-specific somatic instability contributes to disease pathogenesis. In mammalian cells instability of triplet-repeats is dependent on the location of the origin of repli...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025579/ https://www.ncbi.nlm.nih.gov/pubmed/20843782 http://dx.doi.org/10.1093/nar/gkq788 |