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The human Pat1b protein: a novel mRNA deadenylation factor identified by a new immunoprecipitation technique

The complex of the yeast Lsm1p-7p proteins with Pat1p is an important mRNA decay factor that is involved in translational shutdown of deadenylated mRNAs and thus prepares these mRNAs for degradation. While the Lsm proteins are highly conserved, there is no unique mammalian homolog of Pat1p. To ident...

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Detalles Bibliográficos
Autores principales: Totaro, Antonio, Renzi, Fabrizio, La Fata, Giorgio, Mattioli, Claudia, Raabe, Monika, Urlaub, Henning, Achsel, Tilmann
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025581/
https://www.ncbi.nlm.nih.gov/pubmed/20852261
http://dx.doi.org/10.1093/nar/gkq797