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The human Pat1b protein: a novel mRNA deadenylation factor identified by a new immunoprecipitation technique
The complex of the yeast Lsm1p-7p proteins with Pat1p is an important mRNA decay factor that is involved in translational shutdown of deadenylated mRNAs and thus prepares these mRNAs for degradation. While the Lsm proteins are highly conserved, there is no unique mammalian homolog of Pat1p. To ident...
Autores principales: | Totaro, Antonio, Renzi, Fabrizio, La Fata, Giorgio, Mattioli, Claudia, Raabe, Monika, Urlaub, Henning, Achsel, Tilmann |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025581/ https://www.ncbi.nlm.nih.gov/pubmed/20852261 http://dx.doi.org/10.1093/nar/gkq797 |
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