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Evolution of ligand specificity in vertebrate corticosteroid receptors

BACKGROUND: Corticosteroid receptors include mineralocorticoid (MR) and glucocorticoid (GR) receptors. Teleost fishes have a single MR and duplicate GRs that show variable sensitivities to mineralocorticoids and glucocorticoids. How these receptors compare functionally to tetrapod MR and GR, and the...

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Detalles Bibliográficos
Autores principales: Arterbery, Adam S, Fergus, Daniel J, Fogarty, Elizabeth A, Mayberry, John, Deitcher, David L, Lee Kraus, W, Bass, Andrew H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025851/
https://www.ncbi.nlm.nih.gov/pubmed/21232159
http://dx.doi.org/10.1186/1471-2148-11-14